Clinical study on traditional chinese medicine for adverse drug reaction of HAART medication
10.3969/j.issn.1671-8348.2013.22.009
- VernacularTitle:中医药降低高效抗逆转录病毒疗法不良反应的临床疗效观察
- Author:
Jing WANG
;
Pan ZHAO
- Publication Type:Journal Article
- Keywords:
traditional chinese medicine;
HAART;
adverse drug reaction;
CD4
- From:
Chongqing Medicine
2013;(22):2591-2593,2596
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical efficacy of traditional medicine for adverse drug reaction of highly active antiretro-viral therapy(HAART)medication.Methods 60 patients with AIDS received conventional treatment with HAART were randomly divided into the treatment group and control group.Traditional medicine was observed in patients of treatment group for more than 3 months,and several necessary test items were recorded before and after research.Results After therapy,the clinical symptoms weight,Karnofsky performance scale(KPS)and CD4 cells of the patients in two groups was obviously improved.Comparing with the control group,treatment group had better significant efficiency in the symptom,increased CD4 cell(P<0.05)and KPS(P<0.05).Inefficiency of ALT and AST in treatment group was lower than control group,while efficiency and stability had no signifi-cant increase.Inefficiency of WBC,RBC,PLT and MCHC in treatment group was significant higher than control group.Conclusion Traditional medicine combine with HAART for HIV/AIDS can decrease the incidence of adverse drug reaction of HAART medi-cation.For patients,the combination have the efficiency on protecting the safety of prescription and improving the routine blood test.The Traditional medicine may play a role in attenuation and synergy and improve the condition and prognosis of patients.
