Deep brain stimulation of bilateral subthalamic nucleus for Parkinson 's disease
- VernacularTitle:双侧丘脑底核脑深部刺激治疗帕金森病
- Author:
Xiaowu HU
;
Xiaoping ZHOU
;
Laixing WANG
- Publication Type:Journal Article
- Keywords:
Deep brain stimulation;
Parkinson's disease;
S ubthalamic nuclear
- From:
Chinese Journal of Minimally Invasive Surgery
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the efficacy of the dual channel deep brain s timulation (DBS) for Parkinson's disease (PD). MethodsThirte en patients with PD presenting bilateral symptoms underwent dual channel DBS of bilateral subthal amic nucleus. The targets were identified by a combination of MRI scanning and m icroelectrode recording. Unified Parkinson's Disease Rating Scale (UPDRS) scores were evaluated postoperatively.ResultsAll the 13 patients w ere followed for 3 months～3 years, with a mean of 6 3 months. When the pulse generator was tur ned on, UPDRS motor scores showed 62 3% symptomatic improvement (75 5% improve me nt in those responsive to dopaminergic therapy) during the “off” status and 24 2% during the “on” status. No complications occurred.Conclusions DBS of bilateral subthalamic nucleus may significantly improve the motor functions in PD patients.
