Studies on the diagnostic values of the neuron-specific enolase and S-100 protein to Creutzfeldt-Jakob disease
- VernacularTitle:神经元特异性烯醇化酶及S-100蛋白对Creutzfeldt-Jakob病诊断价值的研究
- Author:
Li CUI
;
Shihe LIN
;
Jiexu ZHAO
- Publication Type:Journal Article
- Keywords:
Creutzfeldt Jakob disease Neuron specific enolase S 100 protein
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find an easy to do testing method to diagnose CJD in the early stage.Methods The values of NSE and S 100 protein in the serum and CSF of 10 cases of CJD, 10 cases of non CJD dementia and 10 cases of healthy control were measured by ELISA and sandwich ELISA.while the expression of PrP gene of CJD patients being detected.Results The values of NSE and S 100 protein in the serum and CSF of CJD patients were higher than those of non CJD dementia(all P