Effect of Supplement of BCAA on [~3H] Spiperone Binding to Serotonin_(2A) Receptors of Brain and Platelets in Training Rats
- VernacularTitle:补充支链氨基酸对运动大鼠脑及血小板5-HT_(2A)受体与螺环哌丁苯结合影响的研究
- Author:
Zhuojun QIU
;
Jianmin JI
;
Yuan HUANG
- Publication Type:Journal Article
- Keywords:
5-HT 2A receptor,spiperone
- From:Chinese Journal of Sports Medicine
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
SD rats were sampled and spiperone binding to serotonin2A receptors on brain and platelets were tested before and after a section training or long-term(3 weeks) intensive training using radiolabeled receptor assay. Results showed that there were significant increment of concentration of 5-HT in brain and decrease of 5-HT 2A R density in specific binding sites(B max ) on membranes of brain and platelets post acute intensive exercise. The downregulation of B max of 5-HT 2A R could be prevented by the supplement of BCAA+CHO during 3 weeks' intensive training. There was a positive effect on the delay of central fatigue with the supplement of BCAA+CHO during long-term intensive exercise.
