The dynamic change and its clinical significance of serum neuron-specific enolase in the patients with cerebral stroke
- VernacularTitle:脑卒中患者血清神经元特异性烯醇化酶动态变化及其临床意义
- Author:
Ya HE
;
Guilian ZHANG
;
Qinghua SU
- Publication Type:Journal Article
- Keywords:
Cerebral stroke Neuron-specific enolase
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of the neuron-specific enolase(NSE) in the serum of patients with cerebral stroke in diagnosis, seriousness and evaluation of prognosis. Methods The levels of NSE in the serum of 77 patients with cerebral stroke(36 cases with hemorrhage, 41 cases with infarction) were measured by radio-immunoassay (RIA)method.Results The serum leves of NSE both in cerebral infarction and cerebral hemorrhage patients were obviously higher than those of the control group( P 0.05). In the first week there was a positive correlation between NSE serum level and neurological deficit scores,the volume of haemorrhage, the volume of infarction( P 0.05) . Conclusion The NSE level in serum may be served as a objective index of seriousness and early diagnosis in stroke, but no helpful in differential diagnosis and evaluation of prognosis.
