Diagnostic value of combined detection of CRP and Cys C for early renal function impairment in gout patients
10.3969/j.issn.1671-8348.2013.22.019
- VernacularTitle:血清C-反应蛋白和胱抑素C联合检测对痛风患者早期肾功能损伤的诊断价值
- Author:
Yangchun ZHOU
;
Yunxia LI
;
Yan TANG
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
cystatin C;
gout
- From:
Chongqing Medicine
2013;(22):2619-2620,2623
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of combined detection of c-reactive protein(CRP)and cystatin C(Cys C) for early renal function impairment in gout patients,and to provide clinical reference.Methods Two hundred cases of gout patients were investigated and divided into experimental group and control group:experimental group patients(n=100)were with early renal function impairment and the control group(n=100)were without early renal impairment.The concentration of CRP and Cys C were detected with turbidimetric immunoassay method by OLYMPUS AU 400 automatic biochemistry analyzer.Results Serum CRP and Cys C concentrations of gout patients with early renal function impairment were significantly higher than those of gout patients without early renal function impairment(P<0.05).In the group of gout patients with early renal function impairment,the positive rate of serum CRP(75%)and Cys C(81%)had no significant difference(P>0.05).The positive rate of combination detection of CRP and Cys C was 92%,which was significantly higher than either CRP or Cys C(P<0.05).Conclusion The combination detec-tion of CRP and Cys C can improve diagnostis of early renal function impairment in gout patients.
