Fluoxetine in Treatment of Depression with Stress
- VernacularTitle:伴发生活事件的抑郁症患者临床疗效观察
- Author:
Ping LIU
;
Jihua XIAO
;
Anlin ZHENG
- Publication Type:Journal Article
- Keywords:
psychiatry depression case report fluoxetine apparent life event
- From:
Chinese Mental Health Journal
1988;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To confirm the effectiveness of fluoxetine in treatment of depression associated with apparent life events Method: Sixty-two depressive patients who had a total score of the Life Event Scale of more than 30 were treated with fluoxetine for 6 weeks, diazepam was added if necessary CGI, HAMD and HAMA were used to assess the result Result: At the endpoint, the total score of HAMD decreased from 23?4 at baseline to 10?6, the total score of HAMA was also decreased significantly (23?5 to 10?6) At the meantime, the HAMD sleep factor and CGI severity score were also decreased significantly All above measurements showed improvement at the first week of treatment The adverse effects were mild, with lose of appetite, dry mouth and nausea as the most frequently seen, which had no influence on treatment process Conclusion: Fluoxetine plus diazepam is effective in depressive patients with apparent life events with quick response and mild adverse effects
