Identification and Treatment of Depression in Patients with Functional Dyspepsia
- VernacularTitle:功能性消化不良患者伴抑郁障碍的诊断和治疗
- Author:
Jinliang WANG
;
Hong WEI
- Publication Type:Journal Article
- Keywords:
psychiatry depression case control study functional dyspepsia antidepressant
- From:
Chinese Mental Health Journal
1989;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the rate of depression in patients with functional dyspepsia (FD) and corresponding treatments Method:285 out-patients diagnosed as FD were assessed by two physician trained for depression assessment Depression was diagnosed by criteria of CCMD-2-R Patients with depression were divided into three groups: group A (n=28) received venlafaxine, group B (n=31) received doxepine, group C (n=26) received no antidepressant as control SDS (self-rate depression scale) and FD score were used to assess the effect of antidepressants Result:The rate of depression in our sample was 32% (92/285) Among 92 with depression, 85 consent to participate the study FD scores of both group A and group B decreased after 2 weeks treatment, and were significantly lower than that of group C at the end of 8 weeks The score of SDS in group decreased from the end of second week after treatment, and both group A and group B had significantly lower scores in SDS than group C at the end of 8 weeks Group A had fewer side effects than group B Conclusion:Depression is common in patients with FD Antidepressant can improve FD symptoms as well as depressive symptoms Venlafaxine has fewer side effects than doxepine