?-Irradiation with a liquid ~(188)Re-filled balloon prevents neointimal proliferation in the carotid rabbit
- VernacularTitle:以球囊携带液体~(188)铼兔颈动脉腔内照射预防再狭窄的实验研究
- Author:
Jianguo ZHU
;
Changcong CUI
;
Hanbin CUI
- Publication Type:Journal Article
- Keywords:
Brachytherapy;
Restenosis
- From:
Chinese Journal of Interventional Cardiology
1996;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of ?-irradiation with a liquid 188Re-filled balloon for limiting neointimal proliferation. Methods Balloon overstretch injury was performed in carotid arteries of 12 rabbits and randomly assigned to two groups: the control group (n=6) and the radiation group (n=6), using the liquid 188Re-filled balloon designed to deliver 15 Gy at 0.5 mm from the surface of vessel. All animals survived and were sacrificed in 1 week. Histopathologic analysis was performed. Results The intimal area of radiation group was significantly smaller than that of the control group [(0.04?0.06) mm 2 vs (0.16?0.04) mm 2, P
