Peripheral blood CD34~+ cell absolute count reliably predicts peripheral blood progenitor cell autograft CD34~+ cell content
- VernacularTitle:外周血CD34~+细胞绝对计数可靠预示自体外周血干细胞采集效果
- Author:
Xinan CEN
;
Jianzhong WANG
;
Yongjin SHI
- Publication Type:Journal Article
- Keywords:
Antigens, CD34;
Flow cytometry
- From:
Chinese Journal of Laboratory Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study whether peripheral blood (PB)CD34+ cell absolute count can reliably predict peripheral blood progenitor cell (PBPC) autograft CD34+ cell contents. Methods We examined the PB CD34+ cell count and PBPC CD34+ cell count with ProCOUNT by flow cytometry. Twenty-five collections were performed.The PBPC autograft parameters measured were the CD34+ cell?CFU-GM? CFU-E?BFU-E?CFU-MK and mononuclear cell (MNC) content. We analyzed the correlation between the PB CD34+ cell absolute count?CD34+%?WBC?NEU?MNC?PLT? RBC and Various parameters in the PBPC autograft with Spearman correlations analysis or Regression analysis. Results (1) There is a strong correlation between PB CD34+ cell/L and autograft CD34+ cell/kg (r=0.790,P
