GC Determination of Synthetic Borneol and Menthol in Keyou Nanoemulsion

VernacularTitle:气相色谱法测定克疣纳米乳中冰片和薄荷脑含量
Author: Jingjing FAN ; Yuxia YUAN ; Xiangge YIN ; Wenlong ZHAO ; Yongyan JIA
Publication Type:Journal Article
Keywords: Keyou nanoemulsion; synthetic borneol; menthol; GC
From: Chinese Journal of Information on Traditional Chinese Medicine 2013;(8):52-53,54
CountryChina
Language:Chinese
Abstract: Objective To establish the determination method synthetic borneol and menthol in Keyou nanoemulsion. Methods HP-5 quartz capillary column (30 m×320 μm×0.25 μm) was used with nitrogen as the carrier gas, and FID as the detector. The temperature of the entrance of the capillary vessel column was at 230 ℃. Results Synthetic borneol and menthol in Keyou nanoemulsion were separated well. The calibration curves of synthetic borneol was obtained with good linear relationship within the range of 0.337-1.685 μg (r 2=0.998 2), the average recovery was 97.5%. The calibration curves of menthol was also obtained with a good linear relationship within the range of 0.234-1.17 μg (r 2=0.997 4), the average recovery was 97.0%. Conclusion The methord is simple and accurate. It can be used to control the quality of Keyou nanoemulsion.