Long-term biological variability of serum lipids in Chinese
- VernacularTitle:血脂水平在长时期内的生物学变异
- Author:
Jianzhai LI
;
Wenxiang CHEN
;
Shu WANG
;
Jun DONG
- Publication Type:Journal Article
- Keywords:
Cholesterol;
Triglyceride;
Lipoprotein;
Biological variability
- From:
Chinese Journal of Laboratory Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate long-term biological variability of serum lipids in Chinese. Methods Serum lipids in a Chinese population with relatively stable life styles were monitored with standardized measurements for 1 year (specimens were taken bimonthly) (23 subjects) or 10～15 years (yearly) (100 subjects). Results The total intra-individual variability (analytical and biological variations combined) of total cholesterol, triglycerides, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol averaged 10%, 28%, 16% and 18%, respectively. Conclusion Biological intra-individual variability is a major source of inaccuracy of cardiovascular risk assessments based on lipid measurements. Measures need to be taken to minimize biological variation when medical decisions are to be made in the treatment of lipid disorders.
