Study on pilot preparation of the intradermic distributive system of DHEA by technique of frame work creation fixed on Eudragir E100
- Author:
Nguyen Thanh Hai
- Publication Type:Journal Article
- Keywords:
DHEA
- MeSH:
Dehydroepiandrosterone;
Cosmetic Techniques;
pharmacy
- From:Pharmaceutical Journal
2003;328(8):15-18
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Effects of HPCD and PVP in transdermal delivery systems prepared by combination of Eudragit E100, medium chain triglyceride and isopropyl alcohol on DHEA skin permeation properties were studied. The results were shown that HPCD and PVP have good effects both in permeation properties of DHEA in vitro through pig’s ear stratum corneum and the release properties of DHEA to skin surface. The highest permeation rate reported was about 3.88 mg/cm2.h that indicated the ability of using the patches as a dosage form for administration of DHEA
