Controlled Study on Antidepressant Treatment of Patients with Post-stroke Depression
- VernacularTitle:脑卒中后抑郁患者抗抑郁治疗对照研究
- Author:
Jianxue YANG
;
Yonggang ZHAO
;
Shufeng BAI
- Publication Type:Journal Article
- Keywords:
post-stroke depression antidepressant Paroxetine rehabilitation
- From:
Chinese Mental Health Journal
2002;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of antidepressant in treatment of patients with PSD (post-stroke depression) Method: 121 patients with PSD in their rehabilitation period were stratified by results of HAMD and then randomly divided into two groups, the study group (n=64) received Paroxetine 20 mg daily, the control group (n=57) received placebo After 4 months, the result was assessed with HAMD, CSS and ADL (activity of daily living) Result: In the period of rehabilitation of stroke, the degree of neurological impairment (CSS score) was positively correlated to depression (r=0 99, P