Clinical application of atomoxetine in children with attention deficit hyperactivity disorder
10.3969/j.issn.1000-3606.2009.11.025
- VernacularTitle:托莫西汀在注意缺陷多动障碍儿童中的应用
- Author:
Su YUAN
;
Xu TONG
- Publication Type:Journal Article
- Keywords:
atomoxetine;
attention deficit hyperactivity disorder;
children;
treatment
- From:
Journal of Clinical Pediatrics
2009;(11):1093-1094,1100
- CountryChina
- Language:Chinese
-
Abstract:
Atomoxetine as a nonstimulant medicine was approved by the Chinese Food an Drug Administration and provide a new selection of treatment drugs for attention deficit hyperactivity disorder (ADHD). Tomoxetine is a noradrenaline transmitter reuptake inhibitor which can selectively inhibit synapsis noradrenaline transport protein, strengthen noradrenaline's resupination effect, and increase noradrenaline's activity released by synaptic cleft to improve the symptoms of the ADHD patients. Compared with methylphenidate, atomoxetine does not affect the concentration of the neurotransmitter dopamine and does not induce or increase the Tourettes' syndrome, therefore atomoxetine is more suitable to treat ADHD together with Tourettes syndrome. In this article the treatment of atomoxetine for ADHD, including the indications, dosage as well as adverse reactions and efficacy assessment are reviewed.
