Comparison of emergency percutaneous coronary intervention and intravenous thrombolysis with urokinase combined with emergency percutaneous coronary intervention for acute myocardial infarction
- VernacularTitle:急性心肌梗死急诊介入治疗与静脉溶栓后急诊介入治疗的比较研究
- Author:
Lixian HAN
;
Guisong WANG
;
Zesheng XU
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Urokinase;
Thrombolysis;
Percutaneous coronary intervention
- From:
Chinese Journal of Interventional Cardiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of intravenous thrombolysis with urokinase combined with emergency interventional therapy for acute myocardial infarction(AMI). Methods Fifty two patients with first AMI (≤12 h from onset)were randomized to thrombolysis plus PCI group and primary PCI group,the patency rate of infarct related artery (IRA) before intervention,the procedural success rate,the incidence of bleeding complications and acute ischemic events during hospitalization and the left ventricular ejection fraction (LVEF) measured by echocardiography before discharge were compared.Results The IRA patency rate in the thrombolysis plus PCI group (61 5%) was significantly higher than that in the primary PCI group (19 2%) ( P 0 05),no major bleeding complication and acute ischemic event occurred during hospitalization in both groups,the LVEF in the thrombolysis plus PCI group (64 3?5 6)% was higher than that in the primary PCI group(54 8?4 9)% before discharge ( P
