Assessing the characteristics of coronary hemodynamics in acute hibernating myocardium animal model by intracoronary doppler
- VernacularTitle:冠状动脉内多普勒技术评价急性冬眼心肌动物模型冠状动脉血流动力学特点
- Author:
Dongye LI
;
Defeng PAN
;
Yong XIA
- Publication Type:Journal Article
- Keywords:
Hibernating myocardium;
Intracoronary Doppler;
Coronary dynamic index
- From:
Chinese Journal of Interventional Cardiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the characteristics of coronary hemodynamics in acute hibernating myocardium (AHM) model by intracoronary doppler guidewire. Methods 13 little domestic Chinese swine were established to the model of AHM by interventional method (closed chest),intracoronary Doppler guidewire were used to measure average peak velocity (APV),diastolic systolic velocity ratio (DSVR) and coronary flow velocity reserve (CFVR) distal to the stenosis in the period of pre model,post model and reperfusion.Then animals were executed,the histomography changes of AHM cells were observed.Results 10 animals (76 92%) were established to the model of AHM successfully,myocardium necrosis were not found under microscopical examination.APV and CFVR distal to the stenosis decreased significantly in AHM model ( P