Study on the serum cholesterol regulation of FGS from Lamina- ria japonica Aresch
- VernacularTitle:海带素(FGS)对高胆固醇血症小鼠血清胆固醇的调节作用
- Author:
Aiqin QU
;
Qilin WANG
;
Yinghui ZHANG
- Publication Type:Journal Article
- Keywords:
Fucoidan-galactosan sulfate(FGS);
serum cholesterol
- From:
Chinese Journal of Marine Drugs
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
The hypercholesterolemia model was established by feeding mice on hypercholester-ol diet. FGS was administered to the hypercholesterolemia mice at the dose of 250,750 and 1500mg ? kg-1 ?d-1, respectively. On the 10,20,30 and 40th day, the serum cholesterol was determined. The results were as follows: 40th day the concentration of TC(Ⅰ,Ⅱ,Ⅲ) was 37. 6,54. 2 and 66. 2mg ?dL-1 lower than that of the control group; and the cocentration of LDL-C was 47. 6,86. 6 and 94. 4mg ?dL-1 lower than that of the control group; while the concentration of HDL-C was 16. 1,38. 2 and 36. 7mg?dL-1 higher than that of the control group. It was proved that FGS was an effective serum cholesterol regulator.
