Preliminary study of PON1 gene polymorphism in NIDDM patients with cerebral infarction
- VernacularTitle:Ⅱ型糖尿病并脑梗死患者付氧酶1基因多态性的初步研究
- Author:
Zheng ZHANG
;
Jiang LI
;
Chen ZHANG
- Publication Type:Journal Article
- Keywords:
Paraoxonase Gene Diabetes mellitus Cerebral infarction
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the (PON1) A191B gene polymorphism and NIDDM with or without cerebral infarction (CI).Methods With polymerase chain reaction(PCR) technique,we detected PON1 A191B genotypes in 72 healthy controls,42 NIDDM patients without CI and 45 NIDDM patients with CI.Results There was no relationship between PON1 191 gene B polymorphism and the NIDDM patients without CI,but there was remarkable relationship between it and NIDDM patients with CI (0.78,P