Expression of interleukin 2,interleukin 6,interleukin 2 receptor and Change of T cell in peripheral blood of patients with gynecologic malignancy before and after cord blood transfusion
- VernacularTitle:脐血输注对妇科恶性肿瘤患者外周血中IL-2、IL-6和sIL-2R的诱导表达和T细胞亚群改变
- Author:
Xiaoling PAN
;
Zhilan PEN
;
Yuedong HE
- Publication Type:Journal Article
- Keywords:
Gynecologic Malignancies,Cord blood,Cytokines Support therapy
- From:
Chinese Journal of Blood Transfusion
1988;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the immune function of gynecologic malignant tumor patients with chemotherapy and the influence of cord blood transfusion.Methods Thirty cases of gynecologic malignant tumor patients with chemotherapy and 30 of healthy women were divided into three groups,MTT colorimetry and flow cytometry was used to determine the change of immune function.Results ①The number of CD4 + T cell in patients was lower than that in healthy women and CD8 + was much higher.The ratio of CD4 +/CD8 + was inverted( t=2.56,P