A study on laser channels and myocardial angiogenesis after transmyocardial laser revasculariaztion
- VernacularTitle:激光心肌血运重建术后激光孔道及心肌血管新生的研究
- Author:
Renyao ZHANG
;
Bo SONG
;
Zhao YANG
- Publication Type:Journal Article
- Keywords:
Myocardial revascularization;
Laser;
Myocardial ischemia;
Myocardial infarction;
Angiogenesis
- From:
Chinese Journal of Interventional Cardiology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of traditional transmyocardial laser revascularization (T-TMLR) and non-transmural myocardial laser revascularization (N-TMLR) on myocardial ischemic and necrotic areas and angiogenesis. Methods In rabbit models, using Evans′ blue -TTC stain and HE stain technique for measuring ischemic and necrotic areas and observing angiogenesis. Results After T-TMLR and N-TMLR,compared with the control group, the ischemic areas significantly decreased and significant elevation of angiogenesis was observed. But no difference in necrotic areas was observed among the three groups. Conclusion N-TMLR can achieve the same effects with T-TMLR. Inducing angiogenesis via laser channels and decreasing ischemic area may be one of the predominant mechanisms of TMLR whereas laser channels themselves open or not has no relation to the effects of TMLR.
