Analysis of the expression of cytokines and adherent molecules in 20 cases with aplastic anemia
- VernacularTitle:20例再生障碍性贫血的细胞因子和粘附分子的表达分析
- Author:
Aiying DONG
;
Runtian WANG
;
Liren MA
- Publication Type:Journal Article
- Keywords:
Anemia, aplastic;
Cytokines;
Immunoassays
- From:
Chinese Journal of Laboratory Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of cytokines in hematopoietic microenvironment on the pathogenesis of aplastic anaemia (AA)and its clinical significance Methods For the marrow and peripheral blood samples from 20 AA patients and 8 normal controls, the levels of granulocyte colony stimulating factor (G CSF) and tumor necrosis factor alpha (TNF ?) were determined with ELISA assay,the expression of CD31 and CD44 on the mononuclear cell were measured with immunofluorescence assay Results The level of G CSF and TNF ? in the marrow and blood were higher( P
