Hepatocellular Carcinoma with Cervical Spine and Pelvic Bone Metastases Presenting as Unknown Primary Neoplasm.
- Author:
Seawon HWANG
1
;
Jieun LEE
;
Jung Min LEE
;
Sook Hee HONG
;
Myung Ah LEE
;
Hoo Geun CHUN
;
Ho Jong CHUN
;
Sung Hak LEE
;
Eun Sun JUNG
Author Information
- Publication Type:Case Reports
- Keywords: Hepatocellular carcinoma; Neoplams, unknown primary; Neoplasm metastasis
- MeSH: Antineoplastic Agents/therapeutic use; Bone Neoplasms/*diagnosis/diagnostic imaging/secondary; Carcinoma, Hepatocellular/*diagnosis/drug therapy; Cervical Cord/pathology; Chemoembolization, Therapeutic; Gamma Rays; Humans; Liver Neoplasms/*diagnosis/drug therapy; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasms, Unknown Primary/pathology; Niacinamide/analogs & derivatives/therapeutic use; Pelvic Bones/pathology; Phenylurea Compounds/therapeutic use; Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology 2015;66(1):50-54
- CountryRepublic of Korea
- Language:English
- Abstract: The occurrence of hepatocellular carcinoma (HCC) is closely associated with viral hepatitis or alcoholic hepatitis. Although active surveillance is ongoing in Korea, advanced or metastatic HCC is found at initial presentation in many patients. Metastatic HCC presents with a hypervascular intrahepatic tumor and extrahepatic lesions such as lung or lymph node metastases. Cases of HCC presenting as carcinoma of unknown primary have been rarely reported. The authors experienced a case of metastatic HCC in a patient who presented with a metastatic bone lesion but no primary intrahepatic tumor. This case suggests that HCC should be considered as a differential diagnosis when evaluating the primary origin of metastatic carcinoma.