Research on experimental intracerebral hematoma with haemadipsa yanyuanensis injection
- VernacularTitle:盐源山蛭注射液治疗实验性脑内血肿的研究
- Author:
Wenbin WU
;
Changlin HU
;
Bihua WU
- Publication Type:Journal Article
- Keywords:
Intracerebral hemorrhage Haemadipsa yanyuanensis injecetion Rats
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of purified haemadipsa yanyuanensis injection on promoting intracerebral hematoma in rats and its possible mechanism.Methods We set up the experimental intracerebral hemorrhage (ICH) model in rats by stereotaxically injecting quantitative collagenase into their left caudate nucleuses.The effects of haemadipsa yanyuannesis injection on hematoma volume,neurological function recovery,brain water content(BWC),as well as histopathological changes were observed. BWC was calculated by weighing method,local capillaries were observed by micrangium perfusion.Results The intracerebral hematoma of the rats was reduced significantly( P