Detection of anti-HLA antibodies and its clinical implication after kidney transplantation
- VernacularTitle:肾移植后人类白细胞抗原抗体检测的临床意义
- Author:
Liuyang LI
;
Lijuan HU
;
Min LI
;
Ming ZHAO
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Human Leukocyte Antigen;
Panel reactive antibody
- From:
Chinese Journal of Laboratory Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the level of specific anti human leukocyte antigen IgG antibodies and its effect on renal transplantation Methods Specific anti HLA IgG antibodies of 685 serum samples were measured by the micro enzyme linked immunosorbent assay with Lambda Antigen Tray and Lambda Antigen Tray Mixed Results There were 12% positive recipients of anti HLA IgG antibodies among 685 renal transplantation patients The rates of allografts rejection after transplantation were 50% and obviously higher in the sensitized recipients than in non sensitized ones ( P