Association between M235T polymorphism of the angiotensinogen gene and cerebral infarction
- VernacularTitle:血管紧张素原基因M235T多态性与脑梗死的相关性研究
- Author:
Chen ZHANG
;
Song CHI
- Publication Type:Journal Article
- Keywords:
Angiotensinogen Gene Cerebral infarction PCR
- From:
Journal of Clinical Neurology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between M235T polymorphism of angiotensinogen (AGT) gene and cerebral infarction(CI) in Chinese.Methods AGT gene M235T polymorphism was examined in 75 cases with CI and 48 healthy controls by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP).Results The frequencies of AGT gene T235 allele and 235TT genetype were 0.78 and 0.64 respectively,compared with those of the control group (0.604 and 0.375 respectively ),the difference was significant(? 2=8.82, P
