The relationship between angiotension converting enzyme gene polymorphism and Binswanger's disease in Chinese
- VernacularTitle:血管紧张素转换酶基因多态性与中国人Binswanger病的关系
- Author:
Xu ZHANG
;
Junhui XIA
;
Dexin JIN
- Publication Type:Journal Article
- Keywords:
Binswanger's disease Angiotensin converting enzyme Gene polymorphism Risk factor
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between angiotensin converting enzyme (ACE)gene polymorphism and the risk factors of Binswanger's disease (BD) in Chinese Han nationality.Methods ACE gene insertion/deletion(ID) polymorphism in 111 Chinese Han Nationality patients with BD, 98 patients with hypertension and 102 normal controls were detected by polymorase chain reaction (PCR) technology,serum ACE was measured by colorimetric method,the risk factors of BD and family histories were assessed.Results The DD genotype frequency(0.64) was higher in BD group than in hypertension group (0.31, P
