Prevalence of human T lymphotropic virus infection among blood donors
- VernacularTitle:献血员中人类T淋巴细胞白血病病毒感染的检测
- Author:
Guozhong ZHANG
;
Guozhang XUE
;
Bin LUO
- Publication Type:Journal Article
- Keywords:
HTLV Ⅰ infections;
Blood donors;
Enzyme linked immunosorbent assays
- From:
Chinese Journal of Laboratory Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To obtain the prevalence data on human T Lymphotropic virus (HTLV) infection in 2 339 blood donors of an endemic coastal region of Fujian, China. Methods Serum antibodies to HTLV in the donors were detected by a home made double antigen sandwitch ELISA kit. All the ELISA positive samples were further confirmed by Western blot (WB) and/or polymerase chain reaction (PCR) combined with sequencing. Results Nine samples were confirmed as HTLV 1 infection among the 2 339 donors. A man whose wife is one of the nine was also detected to infect by WB and PCR. Conclusion The prevalence of HTLV infection was 0.38% in the endemic coastal region of Fujian, China.
