Relationship between D2S140 gene polymorphism and type 2 diabetes mellitus
- VernacularTitle:D2S140基因多态性与2型糖尿病的相关性研究
- Author:
Bo BAN
;
Hua WANG
;
Ronghua HE
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus D2S140 gene Short tandem repeat
- From:
Chinese Journal of Diabetes
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the relationship between the polymorphism of D2S140 gene and type 2 diabetes mellitus.Methods D2S140 region polymorphism were analyzed with the polymerase chain reaction and short tandem repeat methods in 103 subjects with type 2 diabetes mellitus and 105 nondiabetic subjects.All subjects were biologically unrelated Chinese without a family history of DM.Results There were 7 alleles ranging from 151bp to 163bp in all subjects.The frequencies were 0.01 to 0.37,2 alleles were more common in diabetic patients than in nondiabetic subjects (RR=16.04, P
