Detection of ? amyloid protein in CSF of senile dementia patients and its significance of diagnosis
- VernacularTitle:脑脊液中?淀粉样蛋白检测对老年期痴呆的诊断意义
- Author:
Xinsheng DING
;
Hong CHENG
;
Xueling ZHANG
- Publication Type:Journal Article
- Keywords:
Senile dementia Cerebrospinal fluid ? amyloid protein ELISA
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the levels of ? amyloid protein(A?/?A 4) in cerebrospinal fluid(CSF) of patients with Alzheimer's disease(AD) and vascular dementia(VD) and its significance of diagnosis.Methods The levels of A? 1 40 and A? 1 42 in CSF of 24 patients with AD, 14 patients with VD and 30 normal controls(NC) were detected by enzyme linked immunosorbent assays(ELISA).Results (1)The levels of A? 1 42 in CSF of AD and VD patients were significantly lower than NC group ( P
