The effect of nimodipine on regional cerebral blood flow,brain edema and clinical change of dosage at the different time after cerebral hemorrhage
- VernacularTitle:尼莫地平对脑出血患者局部脑血流、脑水肿及不同时间用药临床变化的影响
- Author:
Fuqiang GUO
;
Yousong YANG
;
Wenzhong SONG
- Publication Type:Journal Article
- Keywords:
Cerebral hemorrhage Nimodipine Regional cerebral blood flow Brain edema
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe dynamically the effect of nimodipine on regional cerebral blood flow (rCBF),brain edema and clinical change of dosage at the different time in the patients with hypertensive cerebral hemorrhage.Methods 108 patients with hypertensive cerebral hemorrhage were divided into the nimodipine treatment group and the controls randomly,and the treatment group was divided into the group of within 12 h with drug and the group of after 12 h with drug again. All patients were given by dynamic observation of SPECT and clinical curative effect;and they were done by dynamic observation of SPECT and CT taking randomly 10 patients out of the groups of control and treatment.Results The improvement of rCBF,clinical curative effect and edema girdle in the treatment group was significantly better than the control group. Patients of within 12 h with drug also showed better outcome than the patients of after 12 h with drug on clinical curative effect.Conclusion Early stage with nimodipine may be positive factor in the improvement of rCBF,clinical curative effect and lightening edema around the hematoma after hypertensive cerebral hemorrhage.
