Effects of benazepril on Urinary excretion of endothelin-1 in patients with diabetic nephropathy and their clinical significance
- VernacularTitle:苯那普利对糖尿病肾病患者尿液内皮素-1排泌的影响及其意义
- Author:
Hancheng GUO
;
Xiaowen CHEN
;
Liming JIANG
- Publication Type:Journal Article
- Keywords:
Endothelin 1 Diabetic Nephropathy Benazepril
- From:Chinese Journal of Diabetes
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of benazepril on urinary excretion of endothelin 1(Et 1) and the level of plasmic Et 1 (PEt) in patients with diabetes mellitus (DM) and diabetic nephropathy(DN).Methods PEt and 24 hours urinary excretion of Et 1 (UEtV) in 54 patients with DM and 39 patients with DN before and after taking benazepril (7.5～12.5mg/d) for two months were measured using radioimmunoassay method.Results PEt and UEtV in patients with DM were significantly higher than in normal control group ( P
