The role of kinin-system in development-of diabetic nephropathy
- VernacularTitle:激肽系统在实验性糖尿病肾病发展中的作用研究
- Author:
Hebin YAO
;
Changyu PAN
;
Sizhen LU
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy Kinin Kallikrein HOET
- From:
Chinese Journal of Diabetes
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of diabetes on the activation of kinin-system and the role of the system in development of diabetic nephropathy. Methods The TKA activation was measured and the function of kinin-system was changed by the antagonist of bradykinin B2 receptor-HOE 140 and kallikrein. Results The activation of TKA decreased sharply at 18 week in diabetic acts and was much lower than the levels of TKA at & week or in control rats (P
