Role of angiotensin Ⅱ subtype 1 receptor in smooth muscle cells apoptosis after balloon injury to vessel
- VernacularTitle:血管紧张素Ⅱ1型受体在血管球囊损伤后平滑肌细胞凋亡中的作用
- Author:
Geng WANG
;
Guoxiang HE
;
Zhiyuan SONG
- Publication Type:Journal Article
- Keywords:
Angiotensin Ⅱ;
Muscle smooth;
Apopto
- From:
Chinese Journal of Interventional Cardiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mechanism of affecting smooth muscle cells apoptosis after balloon injury to vessel Methods The percentage of vascular smooth muscle cells (VSMC) apoptosis and the expression of angiotensin Ⅱ subtype 1 receptor (AT 1R) was measured by terminal deoxynucleotidyl transferase mediated dUTP biotin nick end labeling (TUNEL) and immunohistochemical technique after balloon injury Results Compared with sham's, the expression of AT 1R protein in vascular media was significantly increased at 3 days after balloon injury ( P
