STUDIES ON SCALE-UP OF NETILMICIN FERMENTATION TECHNOLOGY
- VernacularTitle:奈替米星发酵放大工艺研究
- Author:
Li YANG
;
Lianfen WANG
- Publication Type:Journal Article
- Keywords:
Netilmicin,Fermentation, Scale-up
- From:
Microbiology
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Netilmicin n etabolic characteristics of shaking-flask fermentation were investigated. In 12L glass fermentor, it was showed that phosphate and methionine stimulated growth of mycelia and increased the production of antibiotic.On this basis, netilmicin fermentation had been scaled up successfully according to the standard of the same agitated power per unit volume from 12L fermentor to 5t fermentor.
