PROTECTIVE EFFECTS OF PROPYLENE GLYCOL MANNATE SULFATE ON THE WHOLE CEREBRAL LSCHEMIA/REPERFU-SION INJURY IN RABBITS
- VernacularTitle:甘糖酯对家兔全脑缺血再灌损伤的保护作用
- Author:
Xiumei ZHANG
;
Xinbing WEI
;
Xiaohong SUN
- Publication Type:Journal Article
- Keywords:
propylene glycol mannate sulfate;
whole cerebral ischemia/reperfusioninjury;
malondehyde(MDA);
superoxide dismutase(SOD);
glutathione peroxidase(GSH-Px);
brain water content;
nitric oxide (NO)
- From:
Chinese Journal of Marine Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of propylene glycol mannate sulfate (PGMS) on the lipid peroxide (MDA) , superoxide dismutase (SOD) , glutathion peroxidase (GSH-Px), nitric oxide (NO)and water content in the whole cerebral ischemia/reperfusion injury rabbits induced by four-vessel occlusion,The results show that PGMS can decrease the brain water and MDA, and can increase the SOD and GSH-Px level. No significant effect on the NO level has been detected. The results suggest that the protective effects of PGMS on ischemia/reperfusion injury may be related to its antioxidation.
