The experimental study of local adventitial chitin administration for the prevention of restenosis
- VernacularTitle:血管外周局部应用几丁质预防再狭窄的实验研究
- Author:
Jiyuan CHEN
;
Daosheng ZHENG
;
Shihua ZHANG
- Publication Type:Journal Article
- Keywords:
Chitin Vascular intima Restenosis
- From:
Chinese Journal of Interventional Cardiology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
rabbits were divided randomly into control group ( n =8),pseudo operation group ( n =8) and chitin group ( n =8) with the rabbit iliac artery restenotic models The chitin tubes were localized on the adventitia of restenotic iliac arteries in chitin group but not in pseudo operation group The determinations for the area of neointima,neointima/media area ratio,neointima/media thickness ratio and 3 H TdR incoperation demenstrate that chitin can inhibit intimal proliferation of restenotic iliac artery This findings suggest that local adventitial chitin administration may be effective for the prevention of restenosis
