Experimental Study on TNF-a Gene Expression and Anti-Pulmonary Metastases of Macrophages Activated by New Castle Disease Virus
- VernacularTitle:新城鸡瘟病毒诱导巨噬细胞TNF-?基因表达及其继承性抗肺转移作用的实验研究
- Author:
Lianhua BAI
;
Zhenchao QIAN
- Publication Type:Journal Article
- Keywords:
new castle disease virus;
macrophages;
anti-metastases
- From:
Chinese Journal of Cancer Biotherapy
1995;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The activating effect of NDV-L on murine PEM? in vitro and the anti-metastatic effect of NDV-L-PEM? in vitro against B16 melonoma were investigated. The results showed that NDV-L could not only activate murine PEM? morphologically , but also enhance the TNF-? gene expression. If the activated NDV-L PEM? were adoptively transferred in the B16 melanoma bearing mice, significant inhibiting effect against pulmonary metastases could be exhibited.
