EXPERIMENTAL STUDIES ON THE ANITUMOR EFFECT OF OYSTER EXTRACT
- VernacularTitle:牡蛎提取物抗肿瘤作用的实验研究
- Author:
Ying WANG
;
Anlun MA
;
Huizhen ZHANG
- Publication Type:Journal Article
- Keywords:
Oyster extract;
anti-tumor immunity;
HAC murine hepatic cancer;
human colon cancer;
naked mouse
- From:
Chinese Journal of Marine Drugs
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Balb/c mice with HAC murine hepatic cancer were fed with oyster extract at a daily dose of 0. 2 ml (20 mg) for ten successive days. We found that the tumor-caused decreased immunological indicarors including total T cell number, the ratio of helper T cells, the transformation strength induced by mitogens, and NK activity increased markedly. Compared with the control, mice fed with oyster extract showed prolonged survive and their tumor weight reduced significantly. When mice earring human colon cancer were fed with oyster extract at the same dose for 15 days, the tumor size reduced to 44. 6% of the control tumors. The possiblity that oyster extract inhibits tumor growth by enhencing host immune function, especially killer cell activity, was discussed.
