The influence of taurine on IL-1?induced inhibition of insulin release from rat pancreaticislet cells
- VernacularTitle:牛磺酸对白细胞介素－1?损伤的胰岛细胞分泌的影响
- Author:
Neng ZHANG
;
Haili FANG
;
Ying ZHANG
- Publication Type:Journal Article
- Keywords:
IL-1?;
Insulin;
Taurine
- From:
Chinese Journal of Diabetes
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of taurine on IL-1?induced inhibition of insulin release was investigated with cultured neonatal rat pancreatic islet cells.The results indicated that:①Insulin release, both the basal and glucose-stimulated,could be significantly inhibited by addition of IL-1?(5～20U/ml).②The inhibitory effect of IL-1? on insulin release could be reversed by taurine and this effect was directly related to the dose and action time of taurine.
