Preliminary Investigation on MHC-Nonrestricted Tumorlytic Effect Mediated by CD3AK
- VernacularTitle:CD_3AK细胞介导的MHC非限制性溶瘤作用机制的初步研究
- Author:
Guangxia SHI
;
Yidi CHENG
;
Lianying GUO
- Publication Type:Journal Article
- Keywords:
MHC - nonrestricted tumorlytic effect;
CD3 AK
- From:
Chinese Journal of Cancer Biotherapy
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The result showed that CD3AK induced and expanded in vitro could kill MHC I class - negative K562 (NK - sensitive) and Daudi (NK - resistant) tumor cells in a MHC - nonrestricted manner. Induction of necrosis and / or apoptosis of target cells were responsible for the tumorlytic effect mediated by CD3AK.
