Observation on the Hepatic Histology and Serology Changes in HCV-infected Blood Donors
- VernacularTitle:HCV感染的献血者的肝组织学和血清学变化观察
- Author:
Xuanling SHI
- Publication Type:Journal Article
- Keywords:
HCV-inlection;
Blood donor;
Liver tissue;
Serology.
- From:
Chinese Journal of Blood Transfusion
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Seven asymptomatic blood donors,in whom the infection with HCV was verified,were selected. The time of their infection with HCV was one and a half years. And the research on the hepatic histology and serology indexes of the donors was performed. The liver tissue samples gotten by needle biopsy of liver ware examined under the common microscope and electron microscope,thereby the abnormal hepatic histology manifestation was found, in all the donors. The samples of seven cases have shown the pathological changes characteristic of early stage of viral hepatitis under microscope. The result of examination under electron microscope confirmed that the infected donors were located in early stage of infection,and showed the low grade hepatic histological lesion. The serological examination showed that all the seven cases had normal ALT level,and most of them were HCV RNA-positive and had genotype-II . It is necessary to conduct follow-up observation on the relationship between the changes of serological indexes and the hepatic lesion.
