Protective effects of ischemic preconditioning with normothermia or hypothermia on schemia/reperfusion in-jury in isolated rat hearts
- VernacularTitle:不同温度下缺血预处理对离体大鼠心脏缺血-再灌注损伤的心肌保护
- Author:
Shengxi CHEN
;
Guilin YIN
;
Mingdao YUAN
- Publication Type:Journal Article
- Keywords:
Preconditioning Protection of myocardium Crystalloid cardioplegia Isolated rat heart
- From:
Chinese Journal of Interventional Cardiology
1996;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Using isolated rat hearts perfused on a langendorff apparatus,ischemic preconditioning (IP) was investigated with 5 min normothermic (at 37℃) or hypothermic (at 30 ℃) ischemia, followed by 10 min of reperfusion before the arrest period, as an adjunct to St. Thomas crystalloid cardioplegia during 180 min ischemia. After basline functional data were obtained, IP was induced 1 control hearts underwent no IP. Results showed that IP improved functional recovery from ischemia during 45 min reperfusion in normothermic ischemic preconditioning group (NP) comparing with normothermic control (NC),P
