EFFECT OF FISH OIL ON LEFT VENTRICULAR FUNCTION IN ANESTHETIZED RATS
- VernacularTitle:鱼油中EPA和DHA对麻醉大鼠左室功能的影响
- Author:
Jianzheng ZHOU
;
Baojie WU
;
Xiumei ZHANG
- Publication Type:Journal Article
- Keywords:
fish oil;
EPA and DHA;
left ventricular function;
Isoprenaline (ISO );
?-adrenoceptor
- From:
Chinese Journal of Marine Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of fish oil on the basal left ventricular function and changes of left ventricular function induced by isoprenaline (ISO) was demonstrated in the study. The determination of cardiac performance in vivo showed that supplementation with fish oil (EPA and DMA,70%, 1. 4 mL/kg) had no significant effect on basal cardiac performance,while it could significantly inhibit the gains of +dp/dtmax,Vpm and HR induced by ISCK10 6 mol/L, 10 3 mol/L, 10 4 mol/L) introvenously. The result suggest that supplementation with fish oil have some effects on the function of B-adrenoceptors on rat myocardial membrane.
