EFFECTS OF MARINE FISH OIL ON THE PASMA LIPIDS AND RENAL FUNCTION IN PATIENTS WITH CRF
- VernacularTitle:鱼油多烯康胶囊对慢性肾衰病人血脂及肾功能的影响
- Author:
Yaping FAN
;
Jijie JIANG
;
Tongsun QIAN
- Publication Type:Journal Article
- Keywords:
Chronic renal failure;
hyperlipidemia;
marine fish oil
- From:
Chinese Journal of Marine Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
We examined the effects of marine fish oil, which is rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA),in 22 patients with chronic renal failure (CRF). At 8 weeks treatment,marine fish oil led to decreases in both plasma triglyceride ( -24. 7%) and cholesterol (-14. 8%),and increases in high density lipoprotein and the ratio of apolipoprotein Al/apolipoprotein B. Meanwhile, the endogeneous creatinine clearance was raised by 39. 6%,and the increasing rate of serum creatinine level was slowed down. We conclude that supplementation of co-3 polyunsaturated fatty acids can effectively improve the abnormalities of lipids metabolism in CRF. It is beneficial to retardation of progression of CRF,and to reduction of the risk of cardiovascular complications. We hold that marine fish oil can be used as a supplementary drug in the treatment of CRF.
