The Uses of Granulocyte-Macrophage Colony-Stimulating Factor(GM-CSF) in Leucocytopenia After Chemotherapy in Patients with Malignant Tumor
- VernacularTitle:应用GM-CSF治疗恶性肿瘤化疗后白细胞减少的临床研究
- Author:
Xuejian SHAN
;
Dongling WANG
;
Baojiang LIU
- Publication Type:Journal Article
- Keywords:
malignant tumor;
chemotherapy;
GM-CSF
- From:
Chinese Journal of Cancer Biotherapy
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The present study was designed to confirm the use of GM-CSF, made by the Beijing United Biological Engineering Company, in leucocytopenia after chemotherapy in 12 patients with malignant tumor. In patients with malignant tumor the interval leucocytopenia needed shortened 5 days compared with that in control subjects. At the same time GM-CSF could be resistant to infection significantly, especially in patients with complicated infection, and the antibiotic applying time decreased. In addition, clinical experence had shown that there was no obvious side-effects in general dosage. Thus, these findings indicate that GM-CSF is a kind of essential drug in radical chemotherapy in patients with tumor.
