Research on Preparation of Leukocyte-Poor Platelet Concentrates by Centrifugation
- VernacularTitle:离心法制备少白细胞血小板的研究
- Author:
Zongxiang JIN
- Publication Type:Journal Article
- Keywords:
Centrifugation;
Leukocyte-poor platelet;
Clinical transfusion;
Transfusion-associated febrile reaction
- From:
Chinese Journal of Blood Transfusion
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The platelet concentrates prepared by twofold centrifugation in tight quadruple-bag were subjected to the third centrifugation after their disaggregation to remove white and red blood cells from them. The effect of third centrifugation speed on the efficiency of platelet concentrates was treated. The observation of 65 bags undergoing the third 450Xg centrifugation showed that the white blood cell residual was 0. 07?108/L and the platelet recovery was 52. 5% of the whole blood, with the mediant being (5. 3?1. 6) ?1010per bag.The control study of 18-bag platelet concentrates demonstrated that the third centrifugation had no impact on the quality and extrasomatic function of platelets during their storage. The pH of leukocyte-poor platelet concentrates having been stored for 3 and 5 days was significantly higher than that of common platelet concentrates, making up 7. 2?0. 1,6. 6?0. 4,7. 1?0. 2 and 6. 3?0. 6(P
