A study on the mRNA expression of the glucose transporter gene in the diabetic rats
- VernacularTitle:糖尿病鼠葡萄糖转运蛋白基因mRNA表达的研究
- Author:
Hua WANG
- Publication Type:Journal Article
- Keywords:
Glucose transporter mRNA expression Diabetes mellitus Experimental
- From:
Chinese Journal of Diabetes
1993;0(00):-
- CountryChina
- Language:Chinese
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Abstract:
The study was proceeded on the mRNA expression of the GULT1 and GLUT4 gene in the alloxan diabetic rats by the technique of dot-blot hybridization analysis. The results showed that the levels of the GLUT4 mRNA expression were reduced in diabetic rats while increased in insulin treated diabetic rats. This suggests that the reduced GLUT4 mRNA expression which could affect the quantity of its posttranslational products may be one of the causes of the insulin resistance.