Membrane Oxidation Lesions of Stored Red Cell and Protecting Effect of Antioxidation Enzymes
- VernacularTitle:贮存红细胞膜氧化损伤与抗氧化酶的保护作用
- Author:
Jian KANG
- Publication Type:Journal Article
- Keywords:
Red cells;
ATP;
Membrane;
Activated oxygen;
Antioxidation enzymes
- From:
Chinese Journal of Blood Transfusion
1988;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The experimental study of the lesions of red cell membrane caused by peroxi-dation was performed,indicating that having oxidized by superoxide anions,thered cell lesions in appearance were that there was formed the high molecular pro-tein cross-linked polymer,and the conjugated diene level was increased.And thesimilar feature of oxidation lesions was observed in the stored red cells.It wasshowed that antioxidation enzymes could inhibit the forming of protein cross-linkedpolymer and have certain protecting effect on red cell membrane being subject tolesion.
