Pasteurization of Human plasma ?_2-Macroglobulin Preparation
- VernacularTitle:人血浆■_2-巨球蛋白制品的巴斯德消毒
- Author:
Jingxing WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Blood Transfusion
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The ?_2-macroglobulin(?_2M)pre- paration was pasteurized,using 40g/dl of xylitol as a stabilizer,to reduce the risk of transmission of the viral diseases such as AIDS and hepatitis during the clinical trans- fusion.The ?_2-M preparation,treated by heating at 60℃ for 10 hours, can still preserve fully its trypsin- binding biological activity and im- munological reactivity,and no new antigens were detected,which had the behavior in eleetrophoresis and the catabolic rate in rabbit that were not different from those of the un- heated samples,indicating that the pasteurized ?_2-M preparation still keeps its good native properties.
